Changes in S100A8/A9 and S100A12 and Their Comparison with Other Analytes in the Saliva of Pigs with Diarrhea Due to E. coli

The family of calgranulins includes S100A8 (calgranulin A), S100A9 B), which can appear as a heterodimer known S100A8/A9 or calprotectin, and S100A12 C). These proteins are related to different inflammatory conditions, immune-mediated diseases, sepsis considered biomarkers potential interest. This study aims evaluate if A12 could change in pigs with diarrhea due E. coli compare the changes other analytes order explore possible causes mechanisms involved. For this purpose, panel integrated by inflammation (haptoglobin, inter-alpha trypsin inhibitor 4 (ITIH4), total protein); immune system (adenosine deaminase, ADA); stress (alpha-amylase); tissue damage (lactate lactate dehydrogenase (LDH)); (aldolase) redox status (ferric-reducing ability saliva (FRAS) advanced oxidation protein products (AOPP)) was evaluated. measured showed increases coli. and/or significant correlation magnitude some Further studies should be conducted gain knowledge about practical applications measurements pigs.